Stable radicals are being increasingly utilised in magnetic resonance spectroscopy. The covalent attachment of nitroxide spin probes allows reporting on the local environment. In doubly labelled systems the large dipolar interaction between the electron spins gives access to long range distance measurements. We seek to extend these methods to new spin probes and to multiply labelled systems by studying well defined model systems in parallel to biomolecular applications.

In Nuclear Magnetic Resonance stable and persistent radicals can be employed to boost the polarization of the nuclear spins by bringing the thermal polarization of the electron spins to the nuclei or even utilizing the spin order of optically excited states. Hyperpolarization methods have been demonstrated to increase nuclear spin polarisations by more than four orders of magnitude. Here, our special interest lies exploiting the spin order of unity of transient radical pairs for various applications.

Molecule	Oligomer	Oligomerfound
1 ··	2	2.1(1)
2 ··	2	2.1(1)
3 ···	3	3.1(2)
4 ···	3	3.0(2)
5 ····	4	3.9(2)
6 ·	1	1.0(1)

For further information on research projects contact us directly.

SELECTED RECENT PUBLICATIONS

1. “Theory of Solid-State Photo-CIDNP in the Earth Magnetic Field” G. Jeschke, B. C. Anger, B. E. Bode, J. Matysik, J. Phys. Chem. A 2011 , 115 , 9919-9928.
2. “Pulsed Electron-Electron Double Resonance (PELDOR) Distance Measurements in Detergent Micelles” B. E. Bode, R. Dastvan, T. F. Prisner, J. Magn. Reson. 2011 , 211 , 11-17.
3. “Optimization of Transversal Relaxation of Nitroxides for PELDOR Spectroscopy in Phospholipid Membranes” R. Dastvan, B. E. Bode, M. P. R. Karuppiah, A. Marko, S. Lyubenova, H. Schwalbe, T. F. Prisner,J. Phys. Chem. B 2010 , 114 , 13507-13516.
4. “PELDOR on an Exchange Coupled Nitroxide Copper(II) Spin Pair” B. E. Bode, J. Plackmeyer, M. Bolte, T. F. Prisner, O. Schiemann,J. Organomet. Chem. 2009 , 694 , 1172-1179.
5. “PELDOR measurements on a Nitroxide Labeled Cu(II) Porphyrin: Orientation Selection, Spin-Density Distribution and Conformational Flexibility” B. E. Bode, J. Plackmeyer, T. F. Prisner, O. Schiemann, J. Phys. Chem. A 2008 , 112 , 5064-5073.
6. “Counting the Monomers in Nanometer-Sized Oligomers by Pulsed Electron–Electron Double Resonance” B. E. Bode, D. Margraf, J. Plackmeyer, G. Dürner, T. F. Prisner, O. Schiemann, J. Am. Chem. Soc. 2007, 129, 6736-6745.